In January 2016, The Ohio State University Wexner Medical Center, the College of Medicine, and the Health Science Colleges retained Tripp Umbach to undertake a study to quantify the economic impact of the Wexner Medical Center, its in‐patient and ambulatory clinical services, as well as the research and educational missions of its seven Health Sciences Colleges for the State of Ohio, Franklin County, and the City of Columbus. This study measured the growth in total economic impact of these OSU entities since 2010, quantified the current impact of the OSU entities, and projected the economic impact of the OSU entities after planned expansion programs are complete in 2020 and at maturity in 2025.